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Open Access Research article

Network motif comparison rationalizes Sec1/Munc18-SNARE regulation mechanism in exocytosis

Tian Xia1*, Jiansong Tong2, Shailendra S Rathore3, Xun Gu45 and Julie A Dickerson5*

Author Affiliations

1 Biomedical Informatics Center, Northwestern University, Chicago, IL 60611, USA

2 Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA 50011, USA

3 Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, CO 80309, USA

4 Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA

5 Program of Bioinformatics and Computational Biology, Iowa State University, Ames, IA 50011, USA

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BMC Systems Biology 2012, 6:19  doi:10.1186/1752-0509-6-19

Published: 16 March 2012

Additional files

Additional file 1:

Supplements for yeast and neuronal SM-SNARE network modeling. The file includes: System reactions, equations and parameters used in the models for the in silico experiments and parameter robustness analysis [21,26,40,47,48,50-56].

Format: PDF Size: 299KB Download file

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