Figure 1.

The procedure for screening and analyzing the 4 types of regulatory motifs. The GRNs was combined from TF and miRNA regulatory relationships. According to the types of synergistic regulations between regulators, 4 types of regulatory motifs were screened, single-regulation, co-regulation, crosstalk, and independent. Then, human PINs were utilized to elucidate the significance of the correlations between these 4 types of regulatory motifs and PPIs

Lin et al. BMC Systems Biology 2012 6:18   doi:10.1186/1752-0509-6-18
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