Prediction of HGFR as a possible off-target of torcetrapib. (A) Docked complex of HGFR (PDB code 3UH6) and compound 03X in the best docking pose. (B) Docked complex of HGFR and torcetrapib in the best docking pose. Compound 03X and torcetrapib were in the stick representation, whilst the amino acid residues of HGFR were displayed by solid ribbon style in the line representation. C, H, O, N and F were colored with gray, white, red, blue and brown, respectively.
Fan et al. BMC Systems Biology 2012 6:152 doi:10.1186/1752-0509-6-152