Additional file 1.

Figure S1. A. Intracellular concentrations derived from model simulations considering that kcat of phosphofructokinase (PFK) is 2 times less sensitive to temperature than the other glycolytic enzymes. The symbols refer to simulations of: sinoidal temperature cycles (▵) and linear temperature shifts from 30°C steady-state chemostats (○); batch fermentations at different temperatures (□). The colors indicate the culture temperature at the time of sampling. All concentrations are normalized to the levels under glucose excess conditions at 30°C. B. Intracellular concentrations derived from model simulations considering that kcat of pyruvate kinase (PYK) is 2 times less sensitive to temperature than the other glycolytic enzymes. The symbols refer to simulations of: sinoidal temperature cycles (▵) and linear temperature shifts from 30°C steady-state chemostats (○); batch fermentations at different temperatures (□). The colors indicate the culture temperature at the time of sampling. All concentrations are normalized to the levels under glucose excess conditions at 30°C.

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Cruz et al. BMC Systems Biology 2012 6:151   doi:10.1186/1752-0509-6-151