Global characterization of temporal adaptation-related networks. Transitional behavior of the metabolic network after heat and cold stress perturbation. Heatmap of the Jaccard index from (A) sets of EFMs and (B) sets of dispensable reactions included in the minimal networks from consecutive time-points. A low Jaccard index denotes dissimilarity.
Töpfer et al. BMC Systems Biology 2012 6:148 doi:10.1186/1752-0509-6-148