Table 4

Parameter estimations of the L. lactis model
Simultaneous method Incremental method
<a onClick="popup('http://www.biomedcentral.com/1752-0509/6/142/mathml/M23','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1752-0509/6/142/mathml/M23">View MathML</a> min ΦS min ΦC min ΦS
CPU time (sec) >5 days 3476.89 ± 349.63 976.72 ± 31.01 20.82 ± 2.71
eSSM GO iterations 1662 ± 282 4 ± 1 33 ± 7
ΦC Stiff ODE
    2.20
 ± 8.81 × 10-3
6.18 ± 7.28 × 10-2
ΦS
    2.67
 ± 1.93 × 10-4
1.51 × 103 ± 52.50
    5.79
 ± 9.62 × 10-4

a. None of five runs finished with a relative improvement of the objective function below 1% within the 5-day time limit, after iterating for 60, 147, 93, 79 and 31 times. The corresponding ΦC at termination were 9.31, 7.57, 8.77, 9.39 and 12.9, respectively.

Jia et al.

Jia et al. BMC Systems Biology 2012 6:142   doi:10.1186/1752-0509-6-142

Open Data