Schematic representation of Leukotriene and oxoETE synthesis model (“LOS model”). The reactions occurring with 5-LO are in the dashed red circle. Blue rectangular represents metabolites which are variables of “LOS model”. Pink colour indicates complex of 5-LO and HP. Dashed arrows stand for degradation processes.
Karelina et al. BMC Systems Biology 2012 6:141 doi:10.1186/1752-0509-6-141