Additional file 8.

Predicted metabolic fluxes of substrate uptake and oxygen demand for ATP expenditure in varied substrate availability,<a onClick="popup('http://www.biomedcentral.com/1752-0509/6/114/mathml/M3','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1752-0509/6/114/mathml/M3">View MathML</a>. We simulated a varied substrate availability for four selected substrates, including glucose, oleate, acetoacetate and lactate while demanding a baseline ATP consumption rate (vATPase) of 21.6 mmol·min−1·(l cell)−1. This table lists uptake rates for oxygen, glucose, oleate, acetoacetate, lactate and the resulting total substrate uptake rate for each simulated substrate composition. Efficiency indices ( <a onClick="popup('http://www.biomedcentral.com/1752-0509/6/114/mathml/M4','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1752-0509/6/114/mathml/M4">View MathML</a>) were separately calculated for each simulation. Results are shown for calculated efficiency values ( <a onClick="popup('http://www.biomedcentral.com/1752-0509/6/114/mathml/M5','MathML',630,470);return false;" target="_blank" href="http://www.biomedcentral.com/1752-0509/6/114/mathml/M5">View MathML</a>) greater than 0.6 and given in descending order.

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Karlstädt et al. BMC Systems Biology 2012 6:114   doi:10.1186/1752-0509-6-114