Table 3

Enriched pathway analysis of N-MEG+ using GSEA

R

Gene Set Name

Size

ES

NES

P

FD

Gene Set Description


1

WIELAND_HEPATITIS_B_INDUCED*

96

0.62

3.10

0

0

Up-regulated with adaptive T cell activities in viral clearance

2

LEE_TCELLS3_UP*

103

0.63

3.05

0

0

Up-regulated in immature T cell in CD4+ T cell differentiation

3

CANCER_UNDIFF_META_UP@

69

0.65

3.05

0

0

Up-regulated in undifferentiated tumor cells

4

SERUM_FIBROBLAST_CELLCYCLE&

137

0.59

3.02

0

0

Up-regulated in serum response of fibroblasts (wound healing)

5

BRCA_PROGNOSIS_NEG@

95

0.62

2.98

0

0

Up-regulated in breast tumor cells of negative results (prognosis)


Top five highly enriched pathways are shown. * T cell mediated immune response pathways, & Serum response related pathway, @ Gene sets previously known as bad prognosis. R=rank, P=nominal p-value, FD=FDR q-value.

Kim et al. BMC Systems Biology 2011 5(Suppl 2):S4   doi:10.1186/1752-0509-5-S2-S4

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