Table 2

Comparison of stage transition specific genes

Analysis

N-MEG01 (n=40)

N-MEG12 (n=40)

N-MEG23 (n=40)


+

-

+

-

+

-

MP

2.8×10-4

0.13

0.24

0.13

5.7×10-12

3.8×10-11

RLP

7.7×10-7

1.0×10-15

0.13

0.084

4.8×10-11

2.3×10-6

SVP

5.9×10-4

0.03

0.75

0.53

1.2×10-10

1.4×10-5

OVP

1.2×10-11

9.3×10-13

0.24

0.08

7.8×10-29

2.0×10-17

STM

0.042

0.14

0.97

0.30

0.043

0.035

STN

0.030

3.5×10-6

0.04

0.068

9.4×10-4

0.06

STT

1.8×10-3

2.4×10-10

0.12

0.069

5.9×10-7

0.75

STG

1.1×10-5

6.9×10-9

0.01

0.015

0.11

0.53

Overall Stage

6.6×10-8

2.3×10-20

4.2×10-3

1.4×10-3

7.0×10-8

0.15

Tumor Grade

2.1×10-16

2.9×10-22

7.2×10-6

0.48

1.1×10-42

1.7×10-58


N-MEG2→3 (β=10) showed the best significance in cancer prognosis test sets. While N-MEG0→1was also significantly associated with prognosis and some stages, N-MEG1→2 showed surprisingly insignificant results. MP=prognosis of metastasis, RLP=prognosis of relapse, SVP=prognosis of survival, OVP=overall prognosis, STM=stageM, STN=stageN, STG=stageG.

Kim et al. BMC Systems Biology 2011 5(Suppl 2):S4   doi:10.1186/1752-0509-5-S2-S4

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