Table 2 

Significant associations found in real datasets 

Found by eLSA 
Found by PCC 
Found by both 
Found by eLSA 
Found by PCC 
Found by both 



Dataset 
# of factors 
P ≤ 0.01 
P ≤ 0.01 
P ≤ 0.01 
P ≤ 0.05 
P ≤ 0.05 
P ≤ 0.05 
Q ≤ 0.01 
Q ≤ 0.01 
Q ≤ 0.01 
Q ≤ 0.05 
Q ≤ 0.05 
Q ≤ 0.05 

Microbial 
515 
1643 
3237 
293 
2804 
4242 
658 
C. elegans 
446 
42532 
56605 
39114 
57991 
71799 
54201 


Numbers of significant associations found by the extended Local Similarity Analysis (eLSA) and Pearson’s Correlation Coefficient (PCC) by controlling both the pvalue (P) and the qvalue (Q). The pvalues for eLSA were evaluated by permutations and pvalues for PCC was calculated based on the tdistribution. 

Xia et al. BMC Systems Biology 2011 5(Suppl 2):S15 doi:10.1186/175205095S2S15 