Email updates

Keep up to date with the latest news and content from BMC Systems Biology and BioMed Central.

This article is part of the supplement: 22nd International Conference on Genome Informatics: Systems Biology

Open Access Proceedings

Drug-drug relationship based on target information: application to drug target identification

Keunwan Park and Dongsup Kim*

Author Affiliations

Department of Bio and Brain Engineering, KAIST, 373-1, Guseong-dong, Yuseong-gu, Daejeon, 305-701, Republic of Korea

For all author emails, please log on.

BMC Systems Biology 2011, 5(Suppl 2):S12  doi:10.1186/1752-0509-5-S2-S12

Published: 14 December 2011

Additional files

Additional file 1:

Drug structure similarity histogram for true positive drug pairs (correctly predicted positive drug pairs).

Format: TIF Size: 82KB Download file

Open Data

Additional file 2:

Average success rate for the (known) target identification is shown according to the target rank. The target rank is by the target score and the success ratio represent that the score finds the known targets within the corresponding rank (x-axis).

Format: TIF Size: 64KB Download file

Open Data

Additional file 3:

Correlation between the DRS and the drug similarity score from side effect (SE) information.

Format: DOCX Size: 13KB Download file

Open Data

Additional file 4:

Average numbers of ATC-matching negative drugs are plotted according to the drug ranks by the DRS. All descriptions are the same to Figure 2.

Format: TIF Size: 148KB Download file

Open Data

Additional file 5:

Simple statistics about drug-target interactions are shown.

Format: DOCX Size: 13KB Download file

Open Data