Table 3

Effects of parameters based on leave-one-out cross-validation experiments.

Criteria

σ12

Random Control (%)

Linkage Interval (%)

Genome-wide Scan (%)


Precision

0.001

28.87 (0.70)

31.49

4.41

0.01

29.02 (1.17)

31.77

4.78

0.1

29.39 (0.60)

31.36

5.07

1

28.67 (0.72)

31.20

5.53

10

27.76 (0.62)

29.73

5.35

100

28.59 (1.18)

28.16

5.35


Mean Rank Ratio

0.001

10.23 (0.07)

9.83

9.38

0.01

10.25 (0.11)

9.98

9.41

0.1

10.41 (0.07)

9.49

9.54

1

10.75 (0.09)

9.73

9.91

10

11.14 (0.10)

10.92

10.27

100

12.08 (0.10)

11.95

11.24


AUC

0.001

90.58 (0.10)

90.14

90.55

0.01

90.56 (0.14)

90.40

90.61

0.1

90.40 (0.10)

90.22

90.40

1

90.04 (0.11)

90.18

90.11

10

89.69 (0.10)

89.23

89.86

100

88.74 (0.14)

88.41

88.98


The small domain-domain interaction network composed of the PDB part of the DOMINE database and the diffusion kernel are used to obtain the results. Results for random controls are mean (standard deviation) of 10 validation runs.

Zhang et al. BMC Systems Biology 2011 5:55   doi:10.1186/1752-0509-5-55

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