MC under varying media conditions. Starting from a rich medium, medium components are removed one by one under the condition that biomass production is not disrupted until a minimal medium composition is reached. Mean MC values over 20 simulations are shown for the wild type (blue), fis (red), hns (yellow), and fis/hns double mutant (green) effective gene network. Error bars represent the standard deviation.
Sonnenschein et al. BMC Systems Biology 2011 5:40 doi:10.1186/1752-0509-5-40