Eliminating separation nodes. Blocking matrices as presented to the user for selecting separation nodes in subsequent rounds. Rows and columns proposed for cutting are highlighted in colour. (a) First round (b) Round 5 (c) Final result, after seven rounds and restoring all blocks and reincorporation of superfluous externals. The four non-overlapping blocks represent separation into four subnetworks, the largest two still showing minor internal structure.
Verwoerd BMC Systems Biology 2011 5:25 doi:10.1186/1752-0509-5-25