Table 2

Model parameters

Loss-of-signal

Interference

Parameter

Mean value

Sensitivity

Mean value

Sensitivity

k₁

2.6 ± 2.4

-0.35 ± 0.14

1.2 ± 0.6

-0.48 ± 0.10

k₂

1.4 ± 1.0

0.12 ± 0.08

2.2 ± 1.4

0.32 ± 0.12

k₃

3.6 ± 1.5

-1.0 ± 0.10

1.7 ± 0.9

-0.85 ± 0.13

k₄

1.3 ± 0.9

-0.44 ± 0.10

1.0 ± 0.5

-0.49 ± 0.09

k₅

2.3 ± 1.4

0.33 ± 0.12

2.3 ± 1.4

0.35 ± 0.10

k₆

2.3 ± 1.2

-0.81 ± 0.08

1.8 ± 0.9

-0.77 ± 0.06

k₇

1.2 ± 0.7

0.85 ± 0.13

1.3 ± 0.8

0.91 ± 0.09

K

2.47 ± 1.17

2.5 ± 0.6

2.2 ± 0.9

2.5 ± 0.7

n

5.1 ± 1.3

-0.19 ± 0.04

4.4 ± 1.2

-0.29 ± 0.08

t₁

2.6 ± 1.2

0.61 ± 0.17

0.95 ± 0.48

0.32 ± 0.20

s₁

1.3 ± 0.7

-0.62 ± 0.11

2.3 ± 1.0

-0.69 ± 0.08

t₂

0.77 ± 0.55

0.24 ± 0.12

0.71 ± 0.36

0.21 ± 0.09

s₂

1.9 ± 0.9

-0.67 ± 0.09

2.0 ± 0.9

-0.69 ± 0.05

t₃

1.8 ± 0.9

-0.36 ± 0.21

3.9 ± 2.2

-0.15 ± 0.18

s₃

2.1 ± 1.2

-1.2 ± 0.3

1.5 ± 0.6

-1.1 ± 0.2

t₄

1.6 ± 0.8

1.8 ± 0.1

1.2 ± 0.6

1.6 ± 0.2

s₄

0.65 ± 0.33

-0.76 ± 0.51

0.76 ± 0.35

-0.87 ± 0.59

d_W

2.4 ± 2.2

-0.85 ± 0.12

2.1 ± 1.4

-0.90 ± 0.08

k_W

1.4 ± 1.0

-0.15 ± 0.13

1.3 ± 0.84

-0.088 ± 0.088

k_{3, weak}

0.15 ± 0.13

--

--

--

k₈

--

--

5.6 ± 4.8

--

Model parameter properties for parameter sets remaining after the validation step. Mean value columns: Averages and standard deviations of parameter values. Sensitivity column: Averages and standard deviations of wild type WUS sensitivities (Eq. 21). (loss-of-signal 118 parameter sets, interference 531 parameter sets).

Sahlin et al. BMC Systems Biology 2011 5:2   doi:10.1186/1752-0509-5-2