Figure 5.

Impact of VEGFf on VEGF-Receptor binding differs when VEGFf interacts with VEGFR1 and NP-1. Simulation results for (A) Model 1 (VEGFf can bind to VEGFR1 and NP-1) and (B) Model 2 (VEGFf cannot bind to VEGFR1 and NP-1) 3 h after introduction of VEGF(1 ng/ml or 0.023 nM) and VEGFf to the cell system. VEGF bound to VEGFR1 (open), VEGFR2 (filled), and sum of VEGF bound to VEGFR1, VEGFR2, NRP, and ECM (solid line)

Forsten-Williams et al. BMC Systems Biology 2011 5:170   doi:10.1186/1752-0509-5-170
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