ECM Density Impacts Receptor Binding of VEGF at High Densities. Simulation results following introduction of VEGF (0.023 nM or 1 ng/ml) at time zero. VEGF retained by VEGFR1 (open) or VEGFR2 (filled) after 3 h of VEGF exposure is shown. All other parameter values were at base values (Table 2) except for ECM site density.
Forsten-Williams et al. BMC Systems Biology 2011 5:170 doi:10.1186/1752-0509-5-170