Additional file 6.

The filtered S1 SMILEY output. The table contains the filtered SMILEY S1 output as described in materials and methods. The identified blocked reaction is given in column A. Columns B-J report properties of the blocked reactions i.e., causative dead end metabolites, BiGG confidence scores, cellular compartment, whether or not the blocked reaction is in a cascade, blocked reaction components, associated genes, the metabolic subsystem and the metabolic pathway the blocked reaction occurs in. Columns K-O report properties of the S1 solution i.e. the solution category, the experimentally reported directionality and computed directionalities of blocked reactions having category I reversal solutions, the number of resolving reactions composing the solution and the KEGG identifiers of each resolving reaction. The remaining columns report properties of each individual resolving reaction comprising the SMILEY solution i.e. KEGG identifiers, resolving reaction components, metabolic pathway and subsystem and any associated enzyme commission numbers or known human genes.

Format: XLSX Size: 49KB Download file

Rolfsson et al. BMC Systems Biology 2011 5:155   doi:10.1186/1752-0509-5-155