Open Access Research article

How yeast re-programmes its transcriptional profile in response to different nutrient impulses

Duygu Dikicioglu1, Erkan Karabekmez1, Bharat Rash2, Pınar Pir34, Betul Kirdar1 and Stephen G Oliver13*

Author Affiliations

1 Department of Chemical Engineering, Bogazici University, Bebek 34342, Istanbul, Turkey

2 Faculty of Life Sciences, University of Manchester, M1 9PT, Manchester, UK

3 Cambridge Systems Biology Centre & Department of Biochemistry, University of Cambridge, CB2 1GA, Cambridge, UK

4 Novacta Biosystems Limited, BioPark Hertfordshire, Welwyn Garden City, AL7 3AX, Herts, UK

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BMC Systems Biology 2011, 5:148  doi:10.1186/1752-0509-5-148

Published: 25 September 2011

Additional files

Additional file 1:

Analysis of the transcriptome in response to glucose impulse. The file contains data on the dynamic changes in gene expression levels across the genome, the subset of genes with a significant change in their expression, and the self-organizing maps clustering of the dynamic profiles.

Format: XLS Size: 2.8MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

Clustering of the differentially expressed genes in response to glucose impulse. The file contains the significantly associated process GO terms (if such exist) for the clusters of genes responsive to glucose impulse, as determined via self-organizing maps.

Format: XLS Size: 80KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 3:

Analysis of the transcriptome in response to ammonium impulse. The file contains data on the dynamic changes in gene expression levels across the genome, the subset of genes with a significant change in their expressions, and the self-organizing maps clustering of the dynamic profiles.

Format: XLS Size: 2.5MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 4:

Clustering of the differentially expressed genes in response to ammonium impulse. The file contains the significantly associated process GO terms (if such exist) for the clusters of genes responsive to ammonium impulse, as determined via self-organizing maps.

Format: XLS Size: 83KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 5:

Negative-Positive network analysis. The file contains the reference protein-protein interaction network, the reduced networks for both the glucose and ammonium impulse cases, and the list of modules and hubs in the networks.

Format: XLS Size: 7.3MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data