Statistical evidence of coordinate regulation by miRNAs. a, Pearson correlation distributions of miRNAs that target the same complex (red line) is plotted against the distribution of all observed Pearson correlation values (black dotted line). Also the distributions of excluded Pearson correlations of miRNAs from the same family (blue) and the same cluster (green) are plotted. b, Boxplot for direct interactions of proteins targeted by N miRNAs within a cluster as compared to a null model of N randomly sampled miRNAs, respectively.
Sass et al. BMC Systems Biology 2011 5:136 doi:10.1186/1752-0509-5-136