Validation of differentially expressed genes. Analyses of genes differentially expressed (up- or down-regulated) with a threshold of 2.1-fold (1.1 Log2ratio). Target intersection results: common targets - striped bar, unique targets - rosuvastatin (RSV, orange), fenofibrate (FF, blue), LXR agonist T0901317 (T09, red); A: up-regulated genes; B: down-regulated genes. Common - genes that are common between all three compounds. Similar - genes that are common between any of compound pairs.
Kleemann et al. BMC Systems Biology 2011 5:125 doi:10.1186/1752-0509-5-125