Figure 6.

Retrosynthetic maps for the production in E. coli of A) penicillin G and B) cephalosporin. Compounds in gray are endogenous to the chassis organism (E. coli); enzymatic reactions are represented as circles; branching compounds, which can be produced by more than one biochemical transformation, are (S)-2,3,4,5-tetrahydropyridine-2-carboxylate, L-2-aminoadipate-6-semialdehyde; the target compound is at the bottom of the plot.

Carbonell et al. BMC Systems Biology 2011 5:122   doi:10.1186/1752-0509-5-122
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