Additional file 5.

Figure S2. Sensitivity analysis of the model A. At individual level: The figure shows the sensitivity analysis when changing the Teff and Treg proliferation rates for four different seeds. The X axis corresponds to the maximum Treg proliferation rate, αR, and the Y axis to the maximum Teff proliferation rate αE. The Z axis shows the average relapse intensity reached by activated-Teff cells during a 5 year simulation (Z axis). Each blanket corresponds to a different seed. B. At global level: We realize 200 different simulations per each pair of proliferation rates; Average of 200 different "A" blankets.

Format: DOC Size: 249KB Download file

This file can be viewed with: Microsoft Word Viewer

Vélez de Mendizábal et al. BMC Systems Biology 2011 5:114   doi:10.1186/1752-0509-5-114