Table 2

Data sets analyzed for verification and expansion of the cell proliferation literature model

Data Set

EIF4G1

RhoA

CTNNB1

NR3C1


Data Set ID

GSE11011

GSE5913

PMID15186480

E-MEXP-861


PubMed ID

18426977

17213802

15186480

17901120


Perturbation

EIF4G1 siRNA

RhoA Q63L

constitutive beta-catenin-LEF-1

glucocorticoid receptor null


Control Samples

3 control

8 control

3 control

3 control


Experimental Samples

3 siRNA

7 transfected

3 transgenic

3 null


Microarray Platform

Affymetrix Human Genome U133A 2.0

Affymetrix Mouse Genome U74A v2

Affymetrix Mouse Genome 430A

GE Healthcare CodeLink Mouse Whole Genome Bioarray


Tissue

MCF10A cells

NIH3T3 cells

day 18.5 embryonic lung

day 18.5 embryonic lung


Species

human

mouse

mouse

mouse


# State changes

367

1153

645

144


Westra et al. BMC Systems Biology 2011 5:105   doi:10.1186/1752-0509-5-105

Open Data