Figure 1.

Association network inferred from integrated proteomic and transcriptomic data. The CLR method was used to infer association relationships between proteins on the basis of their abundance profiles (Z score > 6.0). The resulting network was extended by combining with association relationships inferred from transcriptomics data (Z score > 8.0). The network was visualized in Cytoscape. The nodes in the network are colored as follows: black, ribosomal proteins; red, SPI-2 proteins; yellow, SPI-1 proteins; orange, effectors which are secreted through SPI-2 T3SS but not in SPI-2; purple, regulators known to be essential for virulence; blue, targets identified in this study.

Yoon et al. BMC Systems Biology 2011 5:100   doi:10.1186/1752-0509-5-100
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