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This article is part of the supplement: Selected articles from the Third International Symposium on Optimization and Systems Biology

Open Access

Parameter optimization by using differential elimination: a general approach for introducing constraints into objective functions

Masahiko Nakatsui, Katsuhisa Horimoto*, Masahiro Okamoto, Yasuhito Tokumoto and Jun Miyake

BMC Systems Biology 2010, 4(Suppl 2):S9  doi:10.1186/1752-0509-4-S2-S9