Table 2

Functional enrichment analysis for the pathways from GPA1 to PRP39 identified by IFDSD.

Pathways

GO term

Corrected P-value

Pathway Frequency

Genome Frequency

Pathway 1:

Pheromone-dependent signal transduction during conjugation with cellular fusion

1.0285e-8

4/4, 100%

29/5819, 0.4%

Response to pheromone

7.4146e-7

4/4, 100%

101/5819, 1.7%

Filamentous growth

8.2752e-5

3/4, 75%

105/5819, 1.8%

Cell cycle arrest

8.2752e-5

2/4, 50%

12/5819, 0.2%

Pathway 2

Adaptation to pheromone during conjugation with cellular fusion

4.2907e-6

3/4, 75%

15/5819, 0.2%

Negative regulation of signal transduction

2.5475e-5

3/4, 75%

30/5819, 0.5%

Re-entry into mitotic cell cycle after pheromone arrest

4.1196e-5

2/4, 50%

3/5819, 0.0%

Negative regulation of cellular process

1.2814e-4

4/4, 100%

290/5819, 4.9%

Ren et al. BMC Systems Biology 2010 4:72   doi:10.1186/1752-0509-4-72