The effect of gaseous hydrogen secretion on the fermentation product secretion profile of C. thermocellum iSR432. The escape flux of H2 was varied incrementally across the viable range, and FBA was used to determine the maximum growth rate and the concomitant fermentation product escape fluxes, given a cellobiose uptake rate of 2.2472 mmol gDW-1 hr-1. Flux variability analysis was used to determine the full range of ethanol flux (dotted orange lines) possible at each test value.
Roberts et al. BMC Systems Biology 2010 4:31 doi:10.1186/1752-0509-4-31