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Open Access Research article

Robust dynamic balance of AP-1 transcription factors in a neuronal gene regulatory network

Gregory M Miller12, Babatunde A Ogunnaike2, James S Schwaber1 and Rajanikanth Vadigepalli1*

Author Affiliations

1 Daniel Baugh Institute for Functional Genomics and Computational Biology,Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University Philadelphia, PA, 19107, USA

2 Department of Chemical Engineering, University of Delaware Newark, DE, 19716, USA

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BMC Systems Biology 2010, 4:171  doi:10.1186/1752-0509-4-171

Published: 17 December 2010

Additional files

Additional file 1:

Supplementary figures and tables. The file contains the following figures and tables: Figure S1 - Dynamics of Input Kinases and Comparison of AT1RGRN Model Prediction with Experimental Data. Figure S2 - Variance of AT1RGRN-predicted AP-1. Figure S3 - Total-effects and First-Order Sensitivities of AT1RGRN-predicted AP-1. Table S1 - Model Reactions. Table S2 - Mass Balances. Table S3 - AT1RGRN Parameters. Table S4 - Parameter Index Corresponding to Figure S4.

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