Research article
Dynamical modeling of microRNA action on the protein translation process
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* Corresponding author: Andrei Zinovyev andrei.zinovyev@curie.fr
- † Equal contributors
1 Institut Curie, Bioinformatics and Computational Systems Biology Of Cancer, Paris, France
2 INSERM, U900, Paris, F-75248 France
3 Mines ParisTech, Centre for Computational Biology, Fontainebleau, F-77300 France
4 CNRS FRE 2944, Institut André Lwoff, Villejuif, France
5 University of Leicester, Center for Mathematical Modeling, Leicester, UK
6 Institute of Computational Modeling SB RAS, Department of nonequilibrium systems, Krasnoyarsk, Russia
BMC Systems Biology 2010, 4:13 doi:10.1186/1752-0509-4-13
Published: 24 February 2010Additional files
Additional file 1:
Analytical analysis of the case of very inefficient cap structure. In this text we derive an asymptotical solution for the case when k1 is very small corresponding to the case of very inefficient translation initiation (for example, in the case of A-cap structure replacement experiment)
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