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Resolution: standard / high Figure 4.
Effect of increasing ultrasensitivity on mutual fidelity & mutual specificity. MFMS values for networks with CPI, CS, and SC were calculated for 10,000 trials over a
large range of parameters (See below for parameter ranges). MFMS values at the 90th percentile of the distribution were then plotted as a function of degree of various
Hill exponents. (A) Dependence of each type of network on n, the degree of ultrasensitivity in the X pathway, where ultrasensitivity in the Y pathway was set to one, m = 1. (B) Dependence on m, the ultrasensitivity of the Y pathway, where n = 1. (Parameter Ranges):
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Haney et al. BMC Systems Biology 2010 4:119 doi:10.1186/1752-0509-4-119 |