Open Access Highly Accessed Research article

Curating the innate immunity interactome

David J Lynn1*, Calvin Chan2, Misbah Naseer2, Melissa Yau2, Raymond Lo3, Anastasia Sribnaia2, Giselle Ring2, Jaimmie Que2, Kathleen Wee2, Geoffrey L Winsor3, Matthew R Laird3, Karin Breuer3, Amir K Foroushani13, Fiona SL Brinkman3 and Robert EW Hancock2

Author Affiliations

1 Animal & Bioscience Research Department, AGRIC, Teagasc, Grange, Dunsany, Co. Meath, Ireland

2 Centre for Microbial Diseases and Immunity Research, 232 - 2259 Lower Mall, University of British Columbia, Vancouver, British Columbia, V6T 1Z4, Canada

3 Department of Molecular Biology and Biochemistry, 8888 University Drive, Simon Fraser University, Burnaby, British Columbia, V5A 1S6, Canada

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BMC Systems Biology 2010, 4:117  doi:10.1186/1752-0509-4-117

Published: 20 August 2010

Additional files

Additional file 1:

Details of the 2089 human genes which are interaction participants in the InnateDB curated interactome.

Format: XLS Size: 2.6MB Download file

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Additional file 2:

Pathway analysis of the 2089 human genes which are interaction participants in the InnateDB curated interactome revealing which pathways are statistically over-represented in the innate immunity interactome.

Format: XLS Size: 1.1MB Download file

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Open Data

Additional file 3:

Gene Ontology analysis of the 2089 human genes which are interaction participants in the InnateDB curated interactome revealing which GO terms are statistically over-represented in the innate immunity interactome.

Format: XLS Size: 876KB Download file

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Open Data

Additional file 4:

Transcription factor binding site analysis of the 2089 human genes which are interaction participants in the InnateDB curated interactome revealing which transcription factor binding sites are statistically over-represented in the promoter regions of these genes.

Format: XLS Size: 1.2MB Download file

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Open Data

Additional file 5:

MicroRNA target motifs which are statistically over-represented in the 2089 human genes which are interaction participants in the InnateDB curated interactome.

Format: XLS Size: 240KB Download file

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Open Data