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Open Access Highly Accessed Research article

Inferring modules from human protein interactome classes

Elisabetta Marras1, Antonella Travaglione1, Gautam Chaurasia23, Matthias Futschik24 and Enrico Capobianco1*

Author Affiliations

1 CRS4 Bioinformatics Laboratory - Technology Park of Sardinia, Pula (Cagliari), Sardinia - Italy

2 Institute for Theoretical Biology - Humboldt University - Berlin, Germany

3 Max-Delbrück Center for Molecular Medicine - Berlin, Germany

4 Centre of Molecular and Structural Biomedicine - Universidade do Algarve - Faro, Portugal

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BMC Systems Biology 2010, 4:102  doi:10.1186/1752-0509-4-102

Published: 23 July 2010

Additional files

Additional file 1:

GOpvalues. Semi-quantitative evaluation of GO-annotated modules with p-values.

Format: DOC Size: 67KB Download file

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Additional file 2:

tableGOp-valuecomplete. Complete list of GO-annotated modules.

Format: DOC Size: 172KB Download file

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Additional file 3:

overlapscores. Overlap scores computed for MCODE and CFinder modules.

Format: DOC Size: 108KB Download file

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Additional file 4:

tablePathways. Pathway annotation and evaluation for MCODE and CFinder modules.

Format: DOC Size: 81KB Download file

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Additional file 5:

TablesModulewisePvsR. P vs R scores computed for MOCDE and CFinder modules.

Format: DOC Size: 119KB Download file

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Additional file 6:

TablesProteinwisePvsR. P vs R scores computed for MOCDE and CFinder modules (disaggregated by interactome class).

Format: DOC Size: 78KB Download file

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Additional file 7:

MCODEresults. It contains four files: MCODE2coresHTP.txt, MCODE2coresINT.txt, MCODE2coresLIT.txt, MCODE2coresORTHO.txt that report core structure and parameters.

Format: ZIP Size: 22KB Download file

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Additional file 8:

CFinder-results. It contains the complete set of communities retrieved by CFinder from the various interactome classes.

Format: ZIP Size: 82KB Download file

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Additional file 9:

Mapping. Protein labels for all datasets.

Format: TXT Size: 161KB Download file

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Additional file 10:

annotation-description. Notes on the computed p-values.

Format: DOC Size: 45KB Download file

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Additional file 11:

walktrap-results. It contains the complete set of communities retrieved by Walktrap from the various interactome classes.

Format: ZIP Size: 76KB Download file

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