BMC Systems Biology

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Open Access Research article

The capacity for multistability in small gene regulatory networks

Dan Siegal-Gaskins1,2, Erich Grotewold1,2 and Gregory D Smith1,3*

Author Affiliations

1 Mathematical Bioscience Institute, The Ohio State University, Columbus, OH 43210, USA

2 Department of Plant Cellular and Molecular Biology and Plant Biotechnology Center, The Ohio State University, Columbus, OH 43210, USA

3 Department of Applied Science, The College of William and Mary, Williamsburg, VA 23187, USA

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BMC Systems Biology 2009, 3:96 doi:10.1186/1752-0509-3-96

Published: 21 September 2009

Additional files

Additional file 1:

The capacity for multistability in small gene regulatory networks: Supplementary Materials. Additional notes on the mathematical tools used and the role of positive and negative feedback in bistability. Also included are the SR graphs for the one component networks.

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