Table 2

Boolean functions based on literature information.

1

COL1A1.out

= (TGFB1 OR FOS OR JUN) AND NOT (TNF AND (NFKB1 OR ETS1))


2

COL1A2.out

= ((TGFB1 AND JUND) OR JUN) AND NOT (TNF AND (NFKB1 OR ETS1))


3

ETS1.out

= ((TNF AND (ETS1 OR JUN)) OR FOS) AND NOT SMAD4


4

FOS.out

= (TGFB1 OR (TNF AND NFKB1)) AND NOT (JUN AND FOS)


5

JUN.out

= (TNF AND JUN) OR SMAD4


6

JUNB.out

= (TGFB1 AND NFKB1 AND SMAD4) OR (TNF AND NFKB1)


7

JUND.out

= (TGFB1 OR TNF) AND JUND AND NOT FOS


8

MMP1.out

= ((TNF AND (ETS1 OR NFKB1)) OR FOS OR JUND) AND NOT TGFB1


9

MMP3.out

= (TNF AND (ETS1 OR JUN OR NFKB1)) OR FOS OR TGFB1


10

MMP9.out

= TNF AND (ETS1 OR NFKB1)


11

MMP13.out

= (TNF AND (JUN OR NFKB1)) OR FOS OR (TGFB1 AND SMAD4)


12

NFKB1.out

= (TNF AND (ETS1 OR NFKB1)) OR TGFB1


13

SMAD4.out

= TGFB1


14

SMAD7.out

= ((TGFB1 AND SMAD4) OR FOS OR JUN) AND NOT (TNF AND NFKB1)


15

TIMP1.out

= (TGFB1 AND SMAD4) OR (TNF AND (JUN OR JUNB OR JUND OR NFKB1)) OR FOS


16

TGFB1.out

= FOS OR JUND


17

TNF.out

= TNF AND (ETS1 OR JUN OR NFKB1)


Wollbold et al. BMC Systems Biology 2009 3:77   doi:10.1186/1752-0509-3-77

Open Data