Table 2

Comparison of MWC and Adair-Klotz constants for hemoglobin

this paper

Yonetani et al. [16]


7.68 × 10-3

7.20 × 10-3

0.96 × 10-2

1.05 × 10-2

1.52 × 10-2

1.15 × 10-2

2.32 × 10-2

2.33 × 10-2


Experimental and theoretical determination of Adair-Klotz constants (in torr-1) from MWC constants at pH 7.0. KR = 3.0 × 10-2torr-1, KT = 7.0 × 10-3 torr-1, and L = 33, as obtained by Yonetani et al. by fitting data with an MWC equation [16]. We used these to compute K1 to K4 using the equations presented in [7] and here compare them to K1 to K4 obtained by Yonetani et al. by fitting the same data with an Adair-Klotz equation [16]. Note that Yonetani et al. used a slightly modified version of the Adair-Klotz equation, meaning that K1 in [16] corresponds to K1 in [4], K2 in [16] to K2 in [4], K3 in [16] to K3 in [4] and K4 in [16] to 4K4 in [4]. To allow easier comparability, we used Yonetani's notation for this table and labelled the constants , ..., to avoid confusion with the original Klotz notation used everywhere else in this paper.

Stefan et al. BMC Systems Biology 2009 3:68   doi:10.1186/1752-0509-3-68

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