Figure 7.

Signaling pathway inferred from a gene regulatory network. This figure depicts a bow tie inferred from membrane-bound proteins and TFs that were predicted to be active in a gene regulatory network [21]. The proteins in the bottom are the TFs, the proteins at the top are the membrane-bound proteins and the remaining proteins constitute the inferred signaling pathway. Different modules of this pathway are associated with different biological processes, where the core module is associated with exocytosis – a process through which cells direct secretory vesicles out of the cell.