Table 3

List of the top ten significant reporter metabolite and subsystem scores for the gdh1/GDH2 vs. wild type comparison in aerobic conditions.

Reporter metabolite

Z-score

No of reactions*


L-proline [c]

2.71

4

Carbon dioxide [m]

2.51

15

Proton [m]

2.19

51

Glyceraldehyde 3-phosphate [c]

1.93

7

Ubiquinone-6 [m]

1.82

5

Ubiquinol-6 [m]

1.82

5

Ribulose-5-phosphate [c]

1.80

4

Uracil [c]

1.74

4

L-homoserine [c]

1.72

4

Alpha-ketoglutarate [m]

1.71

8


Reporter subsystem

Z-score

No of reactions


Citric Acid Cycle

4.58

7

Pentose Phosphate Pathway

3.29

12

Glycine and Serine Metabolism

2.69

17

Alanine and Aspartate Metabolism

2.65

6

Oxidative Phosphorylation

1.79

8

Thiamine Metabolism

1.54

8

Arginine and Proline Metabolism

1.44

20

Other Amino Acid Metabolism

1.28

5

Glycolysis/Gluconeogenesis

0.58

14

Anaplerotic reactions

0.19

9


*Number of reactions categorized in a subsystem or found to be neighboring each metabolite

Mo et al. BMC Systems Biology 2009 3:37   doi:10.1186/1752-0509-3-37

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