Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
- Equal contributors
1 Sirtris, a GSK company 200 Technology Square, Cambridge, MA, 02139, USA
2 Genstruct Inc, One Alewife Center, Cambridge, MA, 02140, USA
BMC Systems Biology 2009, 3:31 doi:10.1186/1752-0509-3-31Published: 10 March 2009
Additional file 1:
Causal network model knowledgebase. This file contains the knowledge used in this CNM effort.
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Additional file 2:
Supplemental data and legends. Supplemental data and legends contains figures detailing state changes underlying many key nodes that were identified in by CNM but were not described in the main text.
Format: PDF Size: 230KB Download file
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