Table 1

Topological parameters for the metabolic networks of E. coli and Buchnera APS

Bacterium (model)

Reaction graph

Goodness of fit of node distribution2


Path length1

Compound graph

Reaction graph


Mode

Max. path length

No. of unreachable nodes/total no. of nodes (%)

In-degree

Out-degree

Total

In-degree

Out-degree

Total


Buchnera iGT196

8

25

19,493/55,932

(34%)

1.622 (0.448)

2.020 (0.211)

1.700 (0.487)

2.411 (0.115)

2.327 (0.114)

1.701 (0.344)

E. coli iJR904

6

19

108,467/369,056

(29%)

1.911 (0.222)

1.905 (0.212)

1.622 (0.448)

2.104 (0.127)

2.114 (0.112)

1.623 (0.333)


1 number of reactions between every pair of metabolites.

2 In-degree is the number of substrates and out-degree is the number of products for the reaction graph. The value of gamma is shown with the Kolmogorov-Smirnov statistic in parentheses, with critical values (α = 0.01) of 0.050 for E. coli and 0.110 for Buchnera.

Thomas et al. BMC Systems Biology 2009 3:24   doi:10.1186/1752-0509-3-24

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