Table 1

Gene coexpression network topology parameter values and comparisons.

Network

Network topology parameter values¹

nodes

edges

<k>

<C>

<l>

<e>

<b>

MA

4974

10400

4.18 ± 14.24

0.25 ± 0.36

10.77 ± 5.03

20.76 ± 3.06

23,500 ± 145,912

NI

4050

10790

5.33 ± 15.28

0.32 ± 0.37

10.17 ± 5.14

21.48 ± 4.22

17,440 ± 74,032

MA random

7055

181001

51.31 ± 15.21

0.48 ± 0.04

6.16 ± 2.07

11.01 ± 0.12

18,203 ± 7,370

NI random

5351

101215

37.83 ± 9.99

0.48 ± 0.05

6.29 ± 2.11

11.36 ± 0.51

14,140 ± 6,150

Comparison

Observed versus random network topology parameter values²

<k>

<C>

<l>

<e>

<b>

t

P

t

P

t

P

t

P

t

P

MA × NI

0.45

0.65

1.11

0.27

0.68

0.50

1.12

0.26

0.31

0.76

MA × MA random

19.86

2.02E-86

5.34

9.58E-08

7.20

6.30E-13

26.74

4.45E-153

0.30

0.76

NI × NI random

14.49

4.72E-47

3.42

6.23E-04

5.62

1.92E-08

19.01

4.22E-79

0.35

0.72

¹Parameter values are shown for the MA, NI and their corresponding random networks. For each network, the number of nodes (genes) and edges is shown along with average ± standard deviations of the node degree <k>, clustering coefficient <C>, path length <l>, eccentricity <e> and betweeness <b>. ²Average coexpression network parameter values were compared using the Students' ttest; resulting t- and P-values are shown.

Jordan et al. BMC Systems Biology 2008 2:96   doi:10.1186/1752-0509-2-96