BMC Systems Biology

official impact factor 3.57

Open Access Research article

From protein interactions to functional annotation: graph alignment in Herpes

Michal Kolář1,2, Michael Lässig1,3 and Johannes Berg1,3*

Author Affiliations

1 Institut für Theoretische Physik, Universität zu Köln, Zülpicher Straße 77, 50937 Köln, Germany

2 Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Vídeňská 1083, 14220 Praha, Czech Republic

3 Kavli Institute for Theoretical Physics, University of California, Santa Barbara, CA 93106-4030 Santa Barbara, USA

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BMC Systems Biology 2008, 2:90 doi:10.1186/1752-0509-2-90

Published: 28 October 2008

Additional files

Additional file 1:

Supplementary Text. The Supplementary Text [Additional file 1] gives full detail of the graph alignment method. The text further describes the methods used for sequence comparison and for calculations of statistical significance of the presented results.

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Additional file 2:

Supplementary Animation. The Supplementary Animation [Additional file 2] illustrates the network alignment algorithm and shows the intermediate steps between the Figure 2a and Figure 2b. See caption of the Figure 2a,b for the colour coding of the nodes and links.

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