Impact of the solvent capacity constraint on E. coli metabolism

Alexei Vazquez^*¹ , Qasim K Beg^*²^,7 , Marcio A deMenezes³ , Jason Ernst⁴ , Ziv Bar-Joseph⁴ , Albert-László Barabási⁵ , László G Boros⁶ and Zoltán N Oltvai²

¹The Simons Center for Systems Biology, Institute for Advanced Study, Princeton, NJ 08540, USA

²Department of Pathology, University of Pittsburgh, Pittsburgh, PA, 15261, USA

³Instituto de Física, Universidade Federal Fluminense, Rio de Janeiro, 24210, Brazil

⁴Machine Learning Department, Carnegie-Mellon University, Pittsburgh, PA, 15217, USA

⁵Department of Physics and Center for Complex Networks Research, University of Notre Dame, South Bend, IN 46556, USA

⁶SiDMAP, LLC and the UCLA School of Medicine, Los Angeles, CA 90064, USA

⁷Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA

author email corresponding author email* Contributed equally

BMC Systems Biology 2008, 2:7doi:10.1186/1752-0509-2-7


Published:	23 January 2008

Additional files

Additional file 1:

E. coli metabolic reactions and biomass vector

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Additional file 2:

Measured enzyme activity values for various intracellular enzymes of the central carbon metabolism

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Additional file 3:

Dchip Microarray analysis of biomass samples from all five dilution/growth rates

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Additional file 4:

Impact of the solvent capacity constraint on E. coli metabolism

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Additional file 5:

Flux predictions for 710 reactions in the in silico of E. coli metabolism during growth on glucose-limited medium

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Additional file 6:

List of all genes along with their 'b'-numbers showing similar expression profile with query genes.

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