BMC Systems Biology

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A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway

Julio Vera1, Julie Bachmann2, Andrea C Pfeifer2, Verena Becker2, Jose A Hormiga3, Nestor VT Darias3, Jens Timmer4, Ursula Klingmüller2 and Olaf Wolkenhauer1*

Author Affiliations

1 Systems Biology and Bioinformatics Group, Department of Computer Science, University of Rostock. Rostock, Germany

2 Systems Biology of Signal Transduction Group. German Cancer Research Center (DKFZ), Heidelberg, Germany

3 Biochemical Technology Group, Department of Biochemistry and Molecular Biology. University of La Laguna. La Laguna, Spain

4 Physics Institute, University of Freiburg, Freiburg, Germany

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BMC Systems Biology 2008, 2:38 doi:10.1186/1752-0509-2-38

Published: 25 April 2008

Additional files

Additional file 1:

Supplementary material. The additional file contains further information about the model calibration process and some figures complementing the discussion and the model selection.

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