A simple principle concerning the robustness of protein complex activity to changes in gene expression

doi:10.1186/1752-0509-2-1

BMC Systems Biology

Volume 2

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Research article

A simple principle concerning the robustness of protein complex activity to changes in gene expression

Jennifer I Semple¹^* , Tanya Vavouri¹^* and Ben Lehner¹^,2

¹EMBL-CRG Systems Biology Unit, Centre for Genomic Regulation (CRG), UPF, Dr. Aiguader 88, Barcelona 08003, Spain

²Institució Catalana de Recerca i Estudis Avançats (ICREA), Centre for Genomic Regulation, UPF, Dr. Aiguader 88, Barcelona 08003, Spain

author email corresponding author email* Contributed equally

BMC Systems Biology 2008, 2:1doi:10.1186/1752-0509-2-1


Published:	2 January 2008

Additional files

Additional file 1:

Supplementary tables 1 and 2. MIPS protein complexes most enriched for essential genes or genes with over-expression phenotypes (uncorrected p < 0.05).

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