BMC Systems Biology

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Open Access Highly Access Research article

Decision tree modeling predicts effects of inhibiting contractility signaling on cell motility

Sourabh Kharait1, Sampsa Hautaniemi2,3, Shan Wu2, Akihiro Iwabu1, Douglas A Lauffenburger2 and Alan Wells1*

  • * Corresponding author: Alan Wells wellsa@upmc.edu

  • † Equal contributors

Author Affiliations

1 Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA

2 Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, MA 02139, USA

3 Computational Systems Biology Laboratory, Institute of Biomedicine and Genome-Scale Biology Research Program, Biomedicum Helsinki, 00014 University of Helsinki, Finland

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BMC Systems Biology 2007, 1:9 doi:10.1186/1752-0509-1-9

Published: 29 January 2007

Additional files

Additional file 1:

Polynomial estimates and pooled error calculations for model/data fits. Each of the experimental data sets (5 minutes, 1 hour, and 16 hours) involves interpolating polynomials; the polynomials corresponding to each set, and the associated error in model data-fitting, are listed here.

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