Mean to variance correlation. (A) The noise strength (Fano factor) ν of simulated Bicoid molecular number gradient is defined as molecular variance divided by molecular mean . The key indicates that parameters were obtained from (1) the high-variance ensemble of 89 embryos, (2) the low-variance ensemble of 17 embryos, and (3) the extreme condition of high diffusion rate D = 7890 (μm2/s), decay rate ω = 1.0 (s-1) and synthesis rate J = 70000 (molecules/s). (B) As shown in the key, noise strength of simulated fluorescence intensity and rescaled gradient were obtained using parameters from (1) the high-variance ensemble of 89 embryos and (2) the low-variance ensemble of 17 embryos.
Wu et al. BMC Systems Biology 2007 1:52 doi:10.1186/1752-0509-1-52