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Open AccessHighly AccessResearch article

Receptor downregulation and desensitization enhance the information processing ability of signalling receptors

Harish Shankaran1 email, H Steven Wiley2 email and Haluk Resat1 email

1Computational Biology and Bioinformatics Group, Pacific Northwest National Laboratory, Richland WA 99352, USA.

2Biological Sciences Division, Pacific Northwest National Laboratory, Richland WA 99352, USA.

author email corresponding author email

BMC Systems Biology 2007, 1:48doi:10.1186/1752-0509-1-48

Published: 9 November 2007

Additional files

Additional File 1:

Supplementary Methods. Detailed descriptions of numerical and analytical solution methodology and rate constants employed in the mathematical model.

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