Figure 1.

A major challenge in synthetic biology is to rationally select DNA sequences that result in targeted dynamic phenotypes. For example, with simulations using Hy3S [29] we are experimenting with multiple alternative promoter sequences to identify the optimal AND gate synthetic gene network, with tetracycline (atc) and IPTG as inputs and green fluorescence protein (GFP) as output.

Kaznessis BMC Systems Biology 2007 1:47   doi:10.1186/1752-0509-1-47
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